Custom Oligo Synthesis (RUO)

Take advantage of our expertise and experience to manufacture high quality research-grade oligos to your exact specifications with our large selection of probe chemistries, modifications, purification options and manufacturing scales.

PCR probes Custom oligos Oligos in plates Complex oligos, bulk or special requests

Explore our diverse selection of PCR probes

One of the benefits of working with Biosearch Technologies is our extensive probe technology menu. Try multiple probe types early in assay development and select the type that performs best in your specific application considering your oligo sequence.

Learn more about each probe type

Know what you want? Chose from the links below.

Dual-Labeled BHQ Probes	NEW MGB Probes
NEW LNA Probes	BHQplus Probes
Molecular Beacons	Scorpions Primers
BHQnova Probes

Save time and money with ValuMix assays, which consist of probe and primers mixed in a single tube.

ValuMix Assay for Gene Expression & qPCR	ValuMix Assay for SNP Genotyping

Configure exactly what you need for your application

Expand beyond standard qPCR probe chemistries and take advantage of our versatile suite of oligo options to yield the assay performance you need. Our extensive selection of nucleic acid derivatives and specialty building blocks is critical to our ability to synthesize high quality and structurally complex oligos. Build custom oligos for any application, including unlabeled PCR primers, highly modified oligos, or DNA/RNA hybrid sequences.

Build custom oligos

Do you require large numbers of oligos for high-throughput applications?

Order custom oligos in plates that provide cost competitive value without compromising on the quality.

We are recognised as one of the few oligo houses able to achieve quality complex synthesis as well as large scale synthesis. Our dedicated experts will work with you to ensure your complex or large scale project is successful–from consultation to optimising design through production, delivery and post-purchase support.

Large-scale options from 100 nmol to several mmol

Maintaining accuracy and quality can prove challenge when moving from small-scale to large-scale oligo synthesis. Simply scaling up small-scale synthesis is not the answer. Working with Biosearch Technologies gives you access to large-scale expertise and equipment. You can rely on us to deliver high quality, bespoke oligos for your small-scale RUO needs through to the demands of commercial production.

Ordering guidance for complex oligos, large-scale synthesis and special requests

Please use the Excel oligo order forms for special requests, including complex oligos and large-scale synthesis. Enter custom delivery amounts and formulations in the notes column.
For technical assistance and support ordering complex oligos, please contact technical support.

Looking for ISO 13485-compliant oligos? Learn more.

Make it your own with more than 1,000 modifications

We offer an extensive range of modifications, from fluorescent dyes and quenchers to amino groups, ligands and modified bases.

Biosearch Technologies is the inventor of the market-leading Black Hole Quencher™ (BHQ™) as well as the CAL Fluor™ and Quasar™ dyes.

Find the right dye to maximise results using the spectral overlay tool

Additional support and tools

How to order oligos

Option 1: online order tool

Convenient for small numbers of oligos and standard amounts < 100 nmol.

Not available for LNA oligos, MGB oligos or oligos in plates.

Navigate to the appropriate product page:
Access the online ordering tool for the probe type via the “Order now” tab on the product page.
Enter your oligos in the ordering tool.
Click “Add to cart.”
Check out to complete the purchase or request a quote.

Option 2: excel order form

Best for ordering many oligos and/or large amounts ( > 100 nmol).

For MGB oligos

Navigate to the “Order now” tab on MGB probe product page.
Click “Order MGB probes” to download the Excel spreadsheet.
Complete the spreadsheet.
Email the spreadsheet to our Lystrup ordering team (EMEA customers only) or our California ordering team (Rest of world).

For LNA oligos

Download the Excel spreadsheet for Dual-Labeled BHQ probes from the order template library.
Follow the directions on the template page to complete your order.

For all other probe types, including custom oligos and ValuMix assays

Download the Excel spreadsheet that best matches your requirements from the order template library.
Follow the directions on the template page to complete your order.

Seeking a partner for your next project?

We are ready to assist.
Let us know what you are trying to achieve and our expert team will be in contact within a business day to talk through your needs.