Black Hole Quencher® (BHQ®) dyes are highly efficient dark quenchers with broad absorption spectra that get paired with a wide range of proprietary or common fluorophores. The ideal combination of fluorophore and respective BHQ quencher yields a high signal-to-noise ratio resulting in superior data quality. Optimal quenching and pairing versatility makes BHQ-labeled probes an excellent tool in qualitative and quantitative PCR (qPCR) experiments such as single and multiplex gene expression, copy number variation, SNP genotyping, and presence/absence.