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  6. QuickExtract DNA and RNA extraction chemistry technology
 
 
 

Genomic DNA and RNA extraction is a complex, demanding,

and costly process. With QuickExtract, it doesn’t have to be.

Ideal for DNA and RNA screening or genotyping, QuickExtract™ Extraction Kits make the process straightforward and efficient, enabling the rapid extraction of PCR-grade genomic DNA from any sample type. All of this is achieved in 3–8 minutes using a single-tube protocol, eliminating the need for cumbersome equipment like centrifuges or spin columns.

 

QuickExtract DNA and RNA extraction features

  • 3–8 minute quick and easy extraction using a simple, one-tube protocol
  • Produces PCR-ready DNA and RNA for a range of applications on most sample types
  • Integrates easily into automated workflows.
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Explore our bestselling DNA/RNA preparation kits

Experience the versatility and efficiency of QuickExtract:

 

  • Efficient preparation of DNA and RNA from an array of samples -- from hair follicles and feather's quill-end cells to tissue culture cells, buccal cells, zebrafish organs and scales and mouse tail snips.
  • Plays a crucial role in SARS-CoV-2 diagnostics enabling quick and simple extraction of RNA from various virus sample materials such as swabs, saliva and UTM/VTM.
  • Compatible with PCR and RT-PCR analyses such as genomic, transgenic or viral screening in animals.
  • Beneficial for genetic and environmental research.Shop now
From Earth to Space:
Scientists love QuickExtract!
 

Backed by 3000+ citations, QuickExtract is propelling science forward – from fuelling the CRISPR revolution and conquering microbial studies in space to striving to find answers to COVID-19. See how:

 

Fanzor is a eukaryotic programmable RNA-guided endonuclease

Saito, M., Xu, P., Faure, G., Maguire, S., Kannan, S., Altae-Tran, H., Vo, S., Desimone, A., Macrae, R. K., & Zhang, F.
RNA-guided systems, which use complementarity between a guide RNA and target nucleic acid sequences for recognition of genetic elements, have a central role in biological processes in both prokaryotes and eukaryotes.
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Interstrand crosslinking of homologous repair template DNA enhances gene editing in human cells

Ghasemi, H. I., Bacal, J., Yoon, A. C., Tavasoli, K. U., Cruz, C. I., Vu, J. T., Gardner, B. M., & Richardson, C. D.
We describe a strategy to boost the efficiency of gene editing via homology-directed repair (HDR) by covalently modifying the template DNA with interstrand crosslinks.
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Targeting TBK1 to overcome resistance to cancer immunotherapy

Sun et al. (2023)
Here we identify the innate immune kinase TANK-binding kinase 1 (TBK1) as a candidate immune-evasion gene in a pooled genetic screen. Using a suite of genetic and pharmacological tools across multiple experimental model systems, we confirm a role for TBK1 as an immune-evasion gene.
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Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

Yarnall et al. (2022)
We present programmable addition via site-specific targeting elements (PASTE), which uses a CRISPR–Cas9 nickase fused to both a reverse transcriptase and serine integrase for targeted genomic recruitment and integration of desired payloads.
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Real-Time Culture-Independent Microbial Profiling Onboard the International Space Station Using Nanopore Sequencing

Stahl-Rommel, S., Jain, M., Nguyen, H. N., Arnold, R. R., Auñón-Chancellor, S. M., Sharp, G. M., Castro, C. L., John, K. K., Juul, S., Turner, D. J., Stoddart, D., Paten, B., Akeson, M., Burton, A. S., & Castro-Wallace, S. L.
Here, we report on the development, validation, and implementation of a swab-to-sequencer method that provides a culture-independent solution to real-time microbial profiling onboard the ISS.
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Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing

Joung et al. (2020)
Here, we describe a simple test for detection of SARS-CoV-2. The sensitivity of this test is similar to that of reverse-transcription–quantitative polymerase-chain-reaction (RT-qPCR) assays. STOP (SHERLOCK testing in one pot) is a streamlined assay that combines simplified extraction of viral RNA with isothermal amplification and CRISPR-mediated detection.
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A 5-min RNA preparation method for COVID-19 detection with RT-qPCR

Ladha, A., Joung, J., Abudayyeh, O. O., Gootenberg, J. S., & Zhang, F.
RNA extraction has become a bottleneck for detection of COVID-19, in part because of reagent shortages. We present here a rapid protocol that circumvents the need for RNA extraction that is compatible with RT-qPCR-based detection methods.
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Genome engineering using the CRISPR-Cas9 system

Ran, F. A., Hsu, P., Wright, J., Agarwala, V., Scott, D., & Zhang, F.
Here we describe a set of tools for Cas9-mediated genome editing via nonhomologous end joining (NHEJ) or homology-directed repair (HDR) in mammalian cells, as well as generation of modified cell lines for downstream functional studies.
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Need custom support?

QuickExtract offers customised solutions to fit your specific needs. With the ability to lyophilise our products, stabilisation and storage at ambient temperatures is easier than ever before. This means that no matter what your requirements may be, whether you need a solution that's easily transportable or one that can withstand harsh conditions, QuickExtract has got you covered.

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